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Wellness & Vaccines

Vitamin C: What It Really Does for Colds, Skin and Sperm

Vitamin C is probably the most familiar supplement of all. Here is what it really does, what it doesn't, how much is enough and who should be careful with high doses.

Vitamin C: What It Really Does for Colds, Skin and Sperm

Key points

  • Taking vitamin C regularly doesn't prevent colds for most people and only shortens them slightly (about 8% in adults); starting it after you're sick doesn't clearly help.
  • Adult men need 90 mg a day, women 75 mg, smokers about 35 mg more; colorful fruit and vegetables (a guava, peppers, kiwi) usually cover it without pills.
  • Men with past kidney stones, people with kidney disease, iron overload or G6PD deficiency should be careful with high doses; IV vitamin C drips lack good evidence in healthy people.

Vitamin C is probably the supplement Thai people know best; many households always have a tube of effervescent tablets on hand. Our clinic page once wrote that vitamin C helps with everything from clearer skin to performance in bed. This time I want to rewrite it to match the evidence better, so you can spend your money and choose with understanding.

What vitamin C does in the body

Vitamin C (ascorbic acid) is a water-soluble vitamin that humans cannot make themselves. Its main jobs are:

  • Building collagen, the structure of skin, blood vessels, gums and healing wounds
  • Acting as an antioxidant
  • Helping absorb iron from plant foods
  • Working with the immune system

Severe deficiency causes scurvy: bleeding gums and slow-healing wounds. This is very rare, except in people who eat almost no fruit and vegetables, drink heavily or smoke a lot.

Separating beliefs from evidence

ClaimWhat the evidence shows
Prevents coldsA Cochrane review found that taking it regularly does not reduce the chance of catching a cold in the general population, except in people doing very heavy exercise, such as marathon runners.
Helps you get over a cold fasterTaking it regularly shortens colds slightly, by about 8% in adults. Starting it after you are already sick doesn't clearly help.
Better, clearer skinSome topical vitamin C formulas help a little with dark spots. Taking it by mouth only helps people who are deficient.
Improves sperm qualityMost research on antioxidants in infertile men is small and low quality. A larger randomized trial, MOXI (2020), found no improvement in sperm quality or pregnancy rates.
Reduces stress, raises testosterone, treats EDNo good enough evidence to recommend it.
Detoxes you after training or hormone useNo evidence, and it does not reduce the risks of steroids or performance-enhancing drugs (PEDs).

If your problem is ED, infertility or low testosterone, looking for the cause will help far more than any vitamin pill.

DiagramVitamin C: belief vs evidence

Belief

  • Take it and you won't catch colds
  • Improves sperm quality
  • Raises testosterone, fixes ED, relieves stress
  • Detoxes after hormone use

The evidence

  • Regular use doesn't lower the chance of a cold in the general public
  • Colds about 8% shorter with regular use
  • MOXI (2020) found no benefit for sperm
  • No evidence for testosterone, ED or detox

Based on Cochrane reviews and the MOXI study (2020).

How much do you need a day?

GroupRecommended daily amount
Adult men90 mg
Adult women75 mg
SmokersAbout 35 mg extra
Upper limit (don't exceed)2,000 mg

Foods high in vitamin C include guava (half a fruit is already over 100 mg), sweet peppers, kiwi, oranges, papaya, strawberries, broccoli and Chinese kale. Fresh produce is better than long-cooked, because vitamin C breaks down with heat.

The body absorbs a smaller share of vitamin C when you take a lot at once, and the excess is passed out in urine. So a 1,000 mg tablet doesn't give most people much more benefit than 200 mg.

DiagramDaily vitamin C, from enough to too much
75–90 mgAdult requirementWomen 75, men 90; smokers +35 mg
100–500 mgEnough for most peopleIf supplementing; half a guava already exceeds 100 mg
1,000 mgLittle extra benefitAbsorption falls; excess leaves in urine
> 2,000 mgAbove the upper limitDiarrhea, abdominal pain, kidney stone risk in men
LowHigh

Who should be careful with high-dose vitamin C

  • Men who have had kidney stones. A study in Swedish men found that regularly taking vitamin C tablets was linked to about twice the rate of kidney stones, because vitamin C can be converted to oxalate.
  • People with chronic kidney disease
  • People with iron overload (hemochromatosis) or certain blood disorders
  • People with G6PD deficiency. Very high intravenous doses can make red blood cells break down. This condition is fairly common in Thailand and Southeast Asia.
  • Common side effects at high doses are diarrhea, stomach pain and heartburn.

Getting your money's worth

  1. Aim for colorful fruit and vegetables every day. Most people will get enough vitamin C without supplements.
  2. If you do supplement, 100–500 mg a day is enough for most people.
  3. Don't take several brands at once. Check whether your multivitamin, drinks and effervescent tablets already contain vitamin C.
  4. If you are vegetarian, taking vitamin C with meals helps you absorb iron better.

Read the bigger picture on supplements in Wellness and preventive health and Vitamin level testing: is it necessary?

When to see a doctor

If you catch colds unusually often, get repeated infections, have slow-healing wounds, bleeding gums or long-lasting fatigue, there may be another cause that needs checking, such as diabetes, anemia or a weakened immune system. At Dr. Kris Clinic I can review the supplements you take, assess what you really need, and plan care that matches your actual problem. English-speaking consultations are available in Surat Thani and online.

Next step

Want help with this? Three simple steps

Reading is a good start. When you are ready, check where you are, see how a consultation works, then book a time that suits you.

Self-checks are a guide only and do not replace a doctor's assessment. Outcomes vary from person to person, depending on the severity of symptoms, the complexity of the problem and other factors.

Consult Dr. Kris

Preventive health care

Plan check-ups, nutrition and supplements that fit your age and lifestyle.

Frequently asked questions

Does high-dose vitamin C help once I have a cold?

In most studies, starting it after you get sick doesn't clearly help. Rest, fluids and treating the symptoms matter more.

Is taking vitamin C every day for a long time dangerous?

Up to 2,000 mg a day is considered fairly safe for most people. Men who have had kidney stones, people with kidney disease or iron overload should talk to a doctor.

Does vitamin C make sperm stronger?

The evidence is weak, and a large randomized trial found no clear benefit. If you want a baby, have a semen analysis and look for the cause with a doctor.

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References

  1. Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013;(1):CD000980.
  2. Thomas LDK, et al. Ascorbic Acid Supplements and Kidney Stone Incidence Among Men: A Prospective Study. JAMA Intern Med. 2013;173(5):386-388.
  3. Steiner AZ, et al. The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial. Fertil Steril. 2020;113(3):552-560.
  4. NIH Office of Dietary Supplements. Vitamin C: Fact Sheet for Health Professionals (updated 2024).

This article is for education and does not replace diagnosis or treatment by a doctor. If you have symptoms or concerns, please see a doctor.

Dr. Kris ClinicFamily Medicine & Sexual Health Clinic, Surat ThaniLed by Dr. Krida Uakridathikarn · licence 48387

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