Men's Health After 50: Heart, Hormones and Sex in the Silver Years
"I'm just getting old" isn't always the answer. Many changes after 50 can be improved, and some are early warnings that let you prevent serious disease in time.


Key points
- After 50, heart disease, diabetes, prostate problems, muscle and bone loss, depression and sexual problems are all linked, so care should look at the whole man.
- ED often appears 3–5 years before heart disease symptoms; low testosterone is diagnosed only with symptoms plus at least two low morning blood tests, and TRAVERSE found TRT didn't raise major cardiac events but needs monitoring.
- Strength training, protein, vaccines (flu, Shingrix, pneumococcal) and attention to mood matter; chest pain, stroke signs or an erection over 4 hours need emergency care.
I have looked after many men in their 50s and beyond. What I hear most often is, "I'm getting old, Doctor, I guess that's just how it is," whether it's tiring easily, a growing belly, poor sleep or erections that aren't what they used to be. It's true that the body changes, but many of these things are not something you simply have to accept, and some symptoms are warning signs that help us prevent serious disease in time.
Why men over 50 need whole-person care
Men of this age are often the head of the family, work hard and only see a doctor once they are seriously unwell. Conditions that become clearly more common in this period include high blood pressure, diabetes, high cholesterol, heart disease, an enlarged prostate, muscle wasting, thinning bones, depression and sexual problems. They are all connected, so care shouldn't be split into separate pieces.
Heart and vessels
- Blood pressure yearly
- Waist ≤ half your height
- Quit smoking
Muscle and bones
- Strength training 2–3 days/week
- Balance training to prevent falls
Prostate
- Frequent or weak urine flow: ask
- Discuss PSA with a doctor at 55–69
Hormones and sex
- ED can be an early warning of heart disease
- Test hormones when symptoms appear
Vaccines
- Flu every year
- Shingles, pneumonia, tetanus
Mind and brain
- Low or hopeless: call 1323 (Thailand mental-health hotline)
- Check hearing and vision
Heart and blood vessels: priority number one
- Check blood pressure at least once a year, and blood sugar and cholesterol according to risk
- Keep your waist to no more than half your height
- Quit smoking, the modifiable risk factor with the biggest payoff
- Men aged 65–75 who have ever smoked should have a one-time ultrasound to check for an abdominal aortic aneurysm
Muscle, bones and falls
After 50, muscle declines by about 1% a year if you don't use it. Muscle wasting makes falls more likely, diabetes harder to control and recovery from illness slower.
- Strength or resistance training 2–3 days a week, covering the major muscle groups
- Aerobic exercise such as brisk walking, cycling or swimming, 150 minutes a week in total
- Balance training, such as standing on one leg or tai chi
- Protein of about 1.0–1.2 g per kg per day; see Nutrition after 50
- An osteoporosis risk assessment; see Calcium, zinc and vitamin D
Prostate and urinary symptoms
Frequent urination, getting up at night to pee and a weak stream are usually caused by an enlarged prostate, which can be treated with medication or surgery. For PSA testing to screen for prostate cancer, men aged 55–69 are advised to discuss the pros and cons with their doctor first. Men whose father or brother had prostate cancer may start earlier.
Testosterone: understanding it properly
Testosterone levels fall slowly with age, by about 1% a year, but not every man becomes deficient. Testosterone deficiency is diagnosed when there are symptoms, such as lower sex drive, no morning erections, fatigue and low mood, together with low levels on morning blood tests on at least 2 occasions.
The most important recent evidence is the TRAVERSE study (NEJM 2023) in more than 5,000 men aged 45–80 with low testosterone and high cardiovascular risk. It found that testosterone gel did not increase major cardiovascular events compared with placebo, but slightly more atrial fibrillation (AF), acute kidney injury and pulmonary embolism were seen. So it should be used in men with a clear indication and monitored regularly. The details are in What is TRT and who is it for? and Depression or low testosterone: how to tell them apart.
Hormone supplements such as DHEA shouldn't be used on your own, because the evidence in men is weak and there are risks.
TRAVERSE (NEJM 2023): no increase in major cardiac events, but slightly more atrial fibrillation and pulmonary embolism.
Sex life after 50
Sex at this age is still normal and important for happiness. What may change is that you need longer stimulation, erections may not be as full as before, and the recovery time after ejaculation gets longer.
- PDE5 inhibitors such as tadalafil or sildenafil work for most men, as assessed and prescribed by a doctor. They must never be combined with nitrate medicines for heart disease.
- Talking with your partner, adjusting the pace and adding intimacy that isn't focused on penetration help a lot. Try reading Sensate focus: a technique to rebuild intimacy.
- PRP or shockwave treatments for ED still have limited evidence; discuss the pros and cons with a doctor first.
Vaccines to get after 50
- Influenza, once a year
- Shingrix shingles vaccine, 2 doses from age 50
- Pneumococcal vaccine; US guidance in 2024 expanded it to all adults from age 50
- Tetanus–diphtheria every 10 years
Mind and brain
Men often don't talk about sadness or stress, yet suicide rates among middle-aged and older men are several times higher than among women. Retirement, loss or chronic illness are vulnerable times. If you feel hopeless, don't want to do anything or have thoughts of harming yourself, call 1323, Thailand's free 24-hour mental-health hotline (Thai language; ask for English support). Worsening hearing and eyesight are also linked with dementia risk and should be checked and corrected.
How Dr. Kris Clinic cares for men over 50
I work as a family physician, looking at the whole person: assessing heart, diabetes and bone risk, reviewing medicines and vaccines, testing hormones when there are symptoms, assessing and treating sexual problems, and talking about your relationship with your partner, without judgment and in confidence. English-speaking consultations are available.
Go to hospital immediately or call 1669 (Thailand's medical emergency number) if you have chest pain or tightness, breathlessness, weakness on one side of the body, a drooping face, slurred speech, or an erection lasting more than 4 hours.
Related case stories from Dr. Kris
Dr. Kris Case: My First Patient, a Man of 80, and Sex in Later LifeFully assess the heart, other conditions and medicines before low-dose erection medicine, and accept that closeness matters at every ageMedicines and services your doctor may consider
- Testosterone blood test฿800Details & order →
- Sidegra sildenafil 50 mg, GPO (4 tabs)฿350Details & order →
- Talafil-5 tadalafil 5 mg (30 tabs)฿2,990Details & order →
Prices are per pack. Every medicine is prescribed only after a doctor's assessment; your doctor will advise whether it suits you. See all medicines & services
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Frequently asked questions
At 50, does every man's testosterone drop?
Levels fall slowly with age, but not everyone becomes deficient enough to have symptoms. Diagnosis needs both symptoms and at least two morning blood tests.
Does TRT increase the risk of heart attack?
The 2023 TRAVERSE study in men with low testosterone and heart risk found no increase in major cardiac events, but slightly more AF and blood clots in the lungs. So it must be used for a clear indication and monitored closely.
Should men over 50 have a PSA test every year?
Not automatically. Men aged 55–69 are advised to talk with a doctor about the benefits and harms before deciding.
If I have erection problems, should my heart be checked too?
Yes, your cardiovascular risk should be assessed, including blood pressure, blood sugar, cholesterol and smoking, because ED can be an early warning sign of heart disease.
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References
- Lincoff AM, et al. Cardiovascular Safety of Testosterone-Replacement Therapy (TRAVERSE). N Engl J Med. 2023;389:107-117.
- Mulhall JP, et al. Evaluation and Management of Testosterone Deficiency: AUA Guideline (amended 2024). American Urological Association.
- Kobayashi M, et al. Expanded Recommendations for Use of Pneumococcal Conjugate Vaccines Among Adults Aged ≥50 Years: ACIP, United States, 2024. MMWR. 2025;74(1):1-8.
- US Preventive Services Task Force. Abdominal Aortic Aneurysm: Screening (2019) and Prostate Cancer: Screening (2018).
- Vlachopoulos CV, et al. Prediction of cardiovascular events and all-cause mortality with erectile dysfunction: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2013;6(1):99-109.
This article is for education and does not replace diagnosis or treatment by a doctor. If you have symptoms or concerns, please see a doctor.












